Middlesbrough FC and Oxford United have played against each other multiple times in various competitions, including the league and cup matches. As of the current season, the two teams compete in different leagues, with Middlesbrough FC playing in the English Championship and Oxford United competing in League One.

The last time the two teams met was in the EFL Cup in August 2020, with Middlesbrough FC emerging victorious with a 2-1 win. Overall, Middlesbrough FC has had the upper hand in recent meetings between the two clubs, winning the majority of matches.

Both teams have passionate fan bases and matches between Middlesbrough FC and Oxford United are always highly anticipated. The rivalry between the two clubs adds an extra layer of excitement to their encounters on the pitch.